Question: What Is Xanthogranulomatous Pyelonephritis?

What causes Xanthogranulomatous pyelonephritis?

Xanthogranulomatous pyelonephritis is a chronic inflammatory condition that is caused by pyogenic infection of the kidney, usually secondary to staghorn calculi (70% of cases), most commonly by Proteus or E.


What is meant by pyelonephritis?

Acute pyelonephritis is a sudden and severe kidney infection. It causes the kidneys to swell and may permanently damage them. Pyelonephritis can be life-threatening. When repeated or persistent attacks occur, the condition is called chronic pyelonephritis.

What tests are done for pyelonephritis?

To diagnose the problem, your health care provider may use the following tests:A medical history. … Physical exam. … Urinalysis. … Urine culture. … Blood cultures. … Computed tomography (CT scan). … Kidney ultrasound.More items…

What is Xgp?

Xanthogranulomatous pyelonephritis (XGP) is a rare chronic inflammatory disorder of the kidney characterised by an infectious phlegmon arising in the renal parenchyma. It is seen in patients who have urolithiasis, urinary tract infection and immunocompromised status.

What causes chronic pyelonephritis?

Chronic pyelonephritis is characterized by renal inflammation and scarring induced by recurrent or persistent renal infection, vesicoureteral reflux, or other causes of urinary tract obstruction.

What is emphysematous pyelonephritis?

EMPHYSEMATOUS pyelonephritis (EPN) has been defined as a necrotizing infection of the renal parenchyma and its surrounding areas that results in the presence of gas in the renal parenchyma, collecting system, or perinephric tissue.

What is the difference between UTI and pyelonephritis?

A urinary tract infection is inflammation of the bladder and/or the kidneys almost always caused by bacteria that moves up the urethra and into the bladder. If the bacteria stay in the bladder, this is a bladder infection. If the bacteria go up to the kidneys, it is called a kidney infection or pyelonephritis.

What is the most common cause of pyelonephritis?

The main cause of acute pyelonephritis is gram-negative bacteria, the most common being Escherichia coli. Other gram-negative bacteria which cause acute pyelonephritis include Proteus, Klebsiella, and Enterobacter. In most patients, the infecting organism will come from their fecal flora.

What is Xanthogranulomatous inflammation?

Xanthogranulomatous inflammation (XGI) is a rare benign inflammatory disease characterized by aggregation of lipid-laden foamy macrophages. This disease entity has been described in various organs but most commonly in the kidney and gallbladder.

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What is the best treatment for pyelonephritis?

Outpatient oral antibiotic therapy with a fluoroquinolone is successful in most patients with mild uncomplicated pyelonephritis. Other effective alternatives include extended-spectrum penicillins, amoxicillin-clavulanate potassium, cephalosporins, and trimethoprim-sulfamethoxazole.